Eyeshield 21 a weak child and firm named Sena Kobayakawa who enters the high school choice, Deimon Private Senior High School, where his childhood friend Mamori Anezaki school in the previous year. Remarkable ability just physically intense spurt of energy and agility, the result of school life were spent in accordance with the demands of bullies. It was revealed later that a friend, Riku, taught him how to run fast to help him against bullies. His ability to quickly catch the eye of a team of American high school foot ball captain Yoichi Hiruma, who forces Sena to join the Deimon Devil Bats to be running again. To protect the identity of the other teams that want to recruit him, Sena is forced to publicly assume the role of team secretary, and enter the field wearing a helmet equipped with a green eye protection to hide her face under the pseudonym of "Eyeshield 21." Emergency crews initially took part in the football tournament spring ball hoping to win with through the strength of their new "secret weapon." However, a very weak team eliminated early on by the Ojo White Knights, a powerhouse football team that focuses on defense. After Deimon's defeat, the Spring tournament is revealed as secondary in importance to the fall tournament, where the teams compete for the chance to play in the "Christmas Bowl" of high school football league championship. Hiruma, Kurita and Sena regroup and slowly build a real team from other misfits and students looking to define themselves, as Tarō "Monta" Raimon, a baseball player who can only catch, and the Ha-Ha Brothers. Other characters slowly join the team, and the series follows the building and growth of the Deimon Devil Bats and its members as well as many of the opposing team as they all strive to achieve their goal of playing in the Christmas Bowl. After the Christmas Bowl, Japan began to gather the best football players to form a team that will represent Japan at the American Football Youth World Championship, where an MVP will be rewarded NFL contract and $ 3 million. The Japanese team managed to make it to the final against Team America. The result is that last touchdown by Sena at the buzzer tying score, and both teams are declared winners, since no one expected anyone to win against America, but both teams are not satisfied with this and tear straight back onto the field for their own improvised "overtime , "causing chaos with officials. It is not clear which team won the unofficial extra period but Panther Team USA won the MVP trophy aloft, winning the pro contract with the San Antonio Armadillos. This series concludes with Sena captained the Devil Bats when Hiruma and Kurita go off to college. In his final year in high school, Sena is invited to Notre Dame High School by Clifford, thus fulfilling Hiruma's proclamation at the beginning of the series: the famous Eyeshield 21 of Notre Dame High has been born. All the main characters are shown in the last chapter to be in college or playing amateur-league football while maintaining a job.

Series begins with the execution of Gol D. Roger, a man known as the King of Pirates (海贼王, Kaizokuō?). Just before his death, Roger announces that the treasure, One Piece (ひと つなぎ の 大 秘宝 (ワンピース), Wan Pisu?), Will be up for the taking, causing the Great Pirate Era (大 海贼 时代, Dai Kaizoku Jidai?) To start . As a result, pirates countless assigned to the Grand Line to find the treasure. Twenty-two years have passed since Roger's execution, and Monkey D. Luffy, a young pirate inspired by his boyhood idol and powerful pirate Red Haired Shanks, since leaving on a trip from the Blue Ocean East to succeed Roger and find the legendary treasure. In an effort to manage their own crew, the Straw Hat Pirates, he befriended a swordsman named Roronoa Zoro and together, they set sail to find the One Piece. They soon met with Nami, the navigator and thief, Usopp, sniper, and a liar, and Sanji, a womanizing chef, leading to a confrontation with the Buggy the Clown, Captain Kuro and Don Krieg. Later, Luffy meeting Arlong, a fishman and member of the former Sun Pirates who think that fishmen are superior to humans. After Luffy defeated Arlong, Nami joins the crew and the Navy put a bounty on the head of Luffy. After making their way through the Grand Line, Nefeltari group meets Vivi, a princess who wants to help save the country, the Kingdom of Alabasta, from the crime syndicate Baroque Works. They then made friends with the doctor and anthropomorphized reindeer Tony Tony Chopper in Drum Island while. Straw Hat Pirates make their way to Alabasta, leading to a fight with Baroque Works, and their leader, Sir Crocodile. Luffy finally beat Crocodile, freeing Alabasta. Soon after, Nico Robin, an archaeologist and former member of Baroque Works, joins the crew. Also, the gift increases while Luffy Zoro gains after the defeat of Crocodile gifts. They soon meet rookie pirate Blackbeard, whose dream is also to be King of the Pirates. After climbing to the floating island Skypiea, crews will be involved in a war between Skypieans and Shandorians, leading to a confrontation with the island authorities Enel, which has power over electricity. Luffy beat Enel to save Skypiea and end the war. The crew immediately meets Navy Admiral Aokiji, who reveals that Robin is involved in seeking Poneglyphs, stones with markings left by an ancient civilization. This group went to the Water 7, Franky shipbuilders faced cyborg. However, Cipher Pol No. 9, the intelligence agency World Government captures Robin, and theStraw Hat Pirates team with Franky and declare war on the World Government, so the battle between CP9 and its accomplices. End of a long battle with CP9 came to a close when the crew to save Robin, Franky and join their crew. Soon after, the crew helped frame musician named Brook find his shadow, which had been stolen by Gecko Moria.
The crew then prepares to sail to the New World, the second half of the Grand Line, after landing at the Sabaody Archipelago. While there, they befriend Silvers Rayleigh, a former member of Roger's pirate crew who plan to coat their ship so they can travel underwater. The crew eventually be separated during a battle with Bartholomew Kuma in the Sabaody Archipelago, Luffy is sent to Amazon Lily all-female island. When she learned that her brother Portgas D. Ace has been detained in government prison Impel Down, Luffy went there and relieve some of the prison, including Fishman Jimbei. Luffy soon learned that Portgas D. Ace is to be executed at Marineford. However, war broke out between the Navy and a group of pirates led by the legendary pirate, Whitebeard. In the subsequent chaos, Whitebeard and Ace was killed. At the suggestion of Rayleigh, Straw Hat Luffy had to undergo rigorous training regimens, some under the auspices of figures. Two years later, the crew regroups at Sabaody Archipelago and travel to Fishman Island to enter the New World. During this time, a group of fishman pirates appear, seeking supremacy against humans. They organized a coup to decide the fate of the island. However, after Nami forgives Jimbei to release Arlong to East Blue, the Straw Hats beat fishmen pirates, save the island. Straw Hats leave Fishman Island and eventually reached the New World, but not before the start of the feud with one of the four main pirates in the New World, Big Mom. Their first destination in the New World is the island half-burning and half-frozen, Hazard Punk.